»Cardiovascular Clinical Trials 


Penn Heart Failure Study: Collection of blood and clinical information in heart failure patients

Official Title
Penn Heart Failure Study (Zanthine Oxidase, Myocardial Genomics, and Heart Failure)[Protocol Amendment version 6.0, dated 10/20/2008]

Thomas Cappola, MD,ScM


Why is this study being done?
We do not fully understand why patients develop heart failure. Certain conditions, such as high blood pressure and blocked arteries, can cause heart failure. However, many patients develop heart failure without these conditions. We think that certain genes (inherited traits) may make some patients more likely to develop heart failure. The purpose of this study is to find genes that contribute to heart failure.

Who is eligible to participate in this study?
Patients referred to the Heart Failure and Cardiac Transplant Clinic who have been diagnosed with heart failure of any cause are eligible to participate in this study.

Age range?

What is involved with this study?
Comprehensive medical information and blood specimens are collected at the first visit. After this visit, we will call patients every six months to conduct a short telephone interview. During this interview, we will ask patients about their medical condition including their symptoms, medications, and any medical procedures or hospitalizations they may have had in the previous six months.

How long will this study run?
We estimate that up to 5000 subjects will participate in this research study. This study will last at least 5 years. The initial study contact will take place at the time of patients regularly scheduled appointments in the Heart Failure and Cardiac Transplant Clinic. The follow-up visits that occur every six months can be either by telephone or during regular office visits in the clinic if the appointment is near the six month timepoint.

Who can I contact for additional information on this trial?
Kimberly Craig, RN, MS
(215) 662-6900
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