We are asking all adult patients with cardiovascular or metabolic conditions regardless of gender, age, or background to volunteer a blood sample to a DNA bank established by the Penn Cardiovascular Institute at University of Pennsylvania Health System (UPHS). By comparing the DNA of our patients, we hope to determine which genes are responsible for certain cardiovascular conditions.
Patients who receive medical or surgical care for a cardiovascular or metabolic condition within the University of Pennsylvania Health System (UPHS) as an inpatient or outpatient are invited to participate. Participation is strictly voluntary. Patients’ current and future medical care at UPHS will not be affected if they decide not to participate.
Participation consists of one visit that takes approximately 15 to 30 minutes.
Once consent is obtained, a blood sample (30 ml or 2 tablespoons) will be drawn. This blood will be used to both collect DNA encoding for many genes related to cardiovascular disease and/or metabolic conditions and for labs that are related to the risk or treatment of cardiovascular disease, diabetes, metabolic conditions or related disorders.
Each patient's blood specimen will be given a special coded number and will not contain the name of the patient or any other identifying information.
In addition, each patient will complete a short survey form that asks questions about personal and family medical history.
By participating in this study, patients are also agreeing to allow us to review their medical records that are available within the UPHS and collect information that is useful for the objectives of this study. For example: medications, weight, laboratory values, past medical history, past procedures, etc. Collected information from medical records and from the survey form will be stored within a secure research database that will be encrypted. Encryption means converting stored data into a form that will not be understood by unauthorized people.
All participants' health information will be coded and will not include any identifying information. The research database will be accessible only by designated research staff.